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Agrisera
COP1/E3 ubiquitin-protein ligase COP1 Polyclonal Antibody
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COP1/E3 ubiquitin-protein ligase COP1 Antibody (AS20-4399) in WB
Samples: Marker: Precision Plus Protein Dual Color Standards (Bio-Rad, #1,610,394) 1 - Arabidopsis thaliana cop 1-4 mutant 2 - Arabidopsis thaliana 35 S-FLAG-GFP-COP 1/cop 1-4 transgenic line #1 3 - Arabidopsis thaliana 35 S-FLAG-GFP-COP 1/cop 1-4 transgenic line #2 Total protein extracted freshly from 15 seedlings (7-day-old grown under short day condition with 8 h light/16 h dark) with 2 x LaemmLi sample... View More
产品信息
AS20-4399
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
His-tagged recombinant part of COP1 protein from Arabidopsis thaliana, overexpressed in E.coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARABIDOPSIS THALIANA CONSTITUTIVE PHOTOMORPHOGENIC 1; ATCOP1; CONSTITUTIVE PHOTOMORPHOGENIC 1; DEETIOLATED MUTANT 340; DET340; EMB168; EMBRYO DEFECTIVE 168; FUS1; FUSCA 1; T21L14.11; T21L14_11
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