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Proteintech
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Immunogen sequence: QLPVDHILAG SFETAMRLLH DQVGVIQFGP YKQLFLQTYA RGRTTYQALP CLPSMYGYPN RNWKDAGLKN GVPAVGLKLN DLIQRLQLCY QLTTVGKFEE AVEKFRSILL SVPLLVVDNK QEIAEAQQLI TICREYIVGL SVETERKKLP KETLEQQKRI CEMAAYFTHS NLQPVHMILV LRTALNLFFK LKNFKTAATF ARRLLELGPK PEVAQQTRKI LSACEKNPTD AYQLNYDMHN PFDICAASYR PIYRGKPVEK CPLSGACYSP EFKGQICRVT TVTEIGKDVI GLRISPLQFR
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha coat protein; Alpha-coat protein; Alpha-COP; Coatomer subunit alpha; HEP-COP; HEPCOP; proxenin; xenin
基因别名: AILJK; AU040324; COPA; HEP-COP; xenin
UniProt ID: (Human) P53621, (Mouse) Q8CIE6
Entrez Gene ID: (Human) 1314, (Mouse) 12847