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.jpg?time=20220826 "COPS6 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))")
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.jpg?time=20220826?time=20220826 "COPS6 Antibody (MA5-21211) in IHC (PFA)")
产品信息
MA5-21211
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2H5
抗原
COPS6 (AAH02520, 30 a.a. ~ 327 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.2-1.0 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2607105
产品详细信息
Peptide Sequence: VMACGVTGSV SVALHPLVIL NISDHWIRMR SQEGRPVQVI GALIGKQEGR NIEVMNSFEL LSHTVEEKII IDKEYYYTKE EQFKQVFKEL EFLGWYTTGG PPDPSDIHVH KQVCEIIESP LFLKLNPMTK HTDLPVSVFE SVIDIINGEA TMLFAELTYT LATEEAERIG VDHVARMTAT GSGENSTVAE HLIAQHSAIK MLHSRVKLIL EYVKASEAGE VPFNHEILRE AYALCHCLPV LSTDKFKTDF YDQCN
靶标信息
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COP9 constitutive photomorphogenic homolog subunit 6; COP9 signalosome complex subunit 6; H_NH0506M12.12; hVIP; JAB1-containing signalosome subunit 6; MOV34 homolog; MOV34 homolog, 34 kD; SGN6; Vpr-interacting protein
基因别名: COPS6; CSN6; HVIP; MOV34-34KD
UniProt ID: (Human) Q7L5N1
Entrez Gene ID: (Human) 10980
