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Peptide sequence: HPRYSRAVVD YDISIVELSE DISETGYVRP VCLPNPEQWL EPDTYCYITG
Sequence homology: Cow: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 86%; Rat: 92%
CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Atrial natriuretic peptide-converting enzyme; Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; Corin; EC 3.4.21; Heart-specific serine proteinase ATC2; MGC119742; pro-ANP-convertase; Pro-ANP-converting enzyme; PRSC; serine peptidase; serine protease; Transmembrane protease serine 10
基因别名: ATC2; CORIN; CRN; Lrp4; PEE5; TMPRSS10
UniProt ID: (Human) Q2TBD2
Entrez Gene ID: (Human) 10699
分子生物学功能:
apolipoprotein
