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Proteintech
CORO1A Polyclonal Antibody
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产品信息
17760-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CORO1A Fusion Protein Ag12139 (1-461 aa encoded by BC110374)
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSRQVVRSS KFRHVFGQPA KADQCYEDVR VSQTTWDSGF CAVNPKFVAL ICEASGGGAF LVLPLGKTGR VDKNAPTVCG HTAPVLDIAW CPHNDNVIAS GSEDCTVMVW EIPDGGLMLP LREPVVTLEG HTKRVGIVAW HTTAQNVLLS AGCDNVIMVW DVGTGAAMLT LGPEVHPDTI YSVDWSRDGG LICTSCRDKR VRIIEPRKGT VVAEKDRPHE GTRPVRAVFV SEGKILTTGF SRMSERQVAL WDTKHLEEPL SLQELDTSSG VLLPFFDPDT NIVYLCGKGD SSIRYFEITS EAPFLHYLSM FSSKESQRGM GYMPKRGLEV NKCEIARFYK LHERRCEPIA MTVPRKSDLF QEDLYPPTAG PDPALTAEEW LGGRDAGPLL ISLKDGYVPP KSRELRVNRG LDTGRRRAAP EASGTPSSDA VSRLEEEMRK LQATVQELQK RLDRLEETVQ AK (1-461 aa encoded by BC110374)
靶标信息
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: actin-binding; Clabp coronin; Clipin-A; coronin 1; coronin, actin binding protein, 1A; coronin-1; Coronin-1A; coronin-like actin binding protein; Coronin-like protein A; Coronin-like protein p57; FLJ41407; MGC117380; TACO; Tryptophan aspartate-containing coat protein
基因别名: CLABP; CLIPINA; CORO1; CORO1A; HCORO1; IMD8; Lmb3; p57; TACO
UniProt ID: (Human) P31146, (Mouse) O89053, (Rat) Q91ZN1
Entrez Gene ID: (Human) 11151, (Mouse) 12721, (Rat) 155151
actin binding
actin monomer binding
protein binding
protein C-terminus binding
cytoskeletal protein binding
myosin heavy chain binding
protein homodimerization activity
phosphatidylinositol 3-kinase binding
poly(A) RNA binding
actin filament binding
identical protein binding
molecular_function
non-motor actin binding protein
immunological synapse formation
phagolysosome assembly
calcium ion transport
phagocytosis
movement of cell or subcellular component
actin filament organization
regulation of cell shape
actin cytoskeleton organization
positive regulation of cell migration
leukocyte chemotaxis
negative regulation of vesicle fusion
cell-substrate adhesion
uropod organization
regulation of actin cytoskeleton organization
nerve growth factor signaling pathway
positive regulation of T cell proliferation
T cell homeostasis
natural killer cell degranulation
negative regulation of neuron apoptotic process
innate immune response
homeostasis of number of cells within a tissue
positive chemotaxis
negative regulation of actin nucleation
regulation of release of sequestered calcium ion into cytosol
early endosome to recycling endosome transport
cellular response to interleukin-4
regulation of actin polymerization or depolymerization
cell migration
regulation of actin filament polymerization
response to cytokine
positive regulation of T cell activation
biological_process
T cell differentiation
