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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
0.2-1 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide directed towards the N-terminal of human CORT |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Affinity Chromatography |
保存液 |
PBS with 2% sucrose |
内含物 |
0.09% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2610541 |
Peptide sequence: MPLSPGLLLL LLSGATATAA LPLEGGPTGR DSEHMQEAAG IRKSSLLTFL
Sequence homology: Human: 100%
This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cortistatin; cortistatin-14; Cortistatin-17; Cortistatin-29; prepro-cortistatin; preprocortistatin
基因别名: CORT; CST-14; CST-17; CST-29; UNQ307/PRO350
UniProt ID: (Human) O00230
Entrez Gene ID: (Human) 1325
分子生物学功能:
neuropeptide
