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产品信息
PA5-50190
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:15-1:50 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Full length fusion protein of Human COX7B2 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.7 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635643 |
产品详细信息
The antibody detects endogenous levels of total COX7B2 protein.
靶标信息
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7b (cytochrome c oxidase subunit VIIb polypeptide) and COX7b2 (cytochrome c oxidase subunit VIIb polypeptide 2) are 80 and 81 amino acid proteins, respectively, which exist as components of the COX complex, therefore playing an important role in electron transport. A rare polymorphism in the COX7b2 gene at codon 26 may be linked to nasopharyngeal carcinoma (NPC), the most common head and neck cancer in southern China.
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生物信息学
蛋白别名: Cytochrome c oxidase polypeptide VIIb2; Cytochrome c oxidase subunit 7B2, mitochondrial; cytochrome c oxidase subunit VIIb2
基因别名: COX7B2
UniProt ID: (Human) Q8TF08
Entrez Gene ID: (Human) 170712
分子生物学功能:
oxidase
