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产品信息
PA5-50191
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:10-1:50 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Fusion protein corresponding to a region derived from internal residues of human cytochrome c oxidase subunit VIIIA (ubiquitous) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635644 |
产品详细信息
The antibody detects endogenous levels of total COX8A protein.
靶标信息
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms. COX8 exists as three isoforms: COX8a, a liver and heart isoform, Cox8b, a heart-specific isoform, and Cox8c, whose expression pattern has yet to be elucidated. All three Cox8 isoforms exists as components of the COX complex and play an important role in electron transport.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2; cytochrome c oxidase subunit 8A (ubiquitous); Cytochrome c oxidase subunit 8A, mitochondrial; cytochrome c oxidase subunit VIII; cytochrome c oxidase subunit VIIIA (ubiquitous)
基因别名: COX; COX8; COX8-2; COX8A; COX8L; VIII; VIII-L
UniProt ID: (Human) P10176
Entrez Gene ID: (Human) 1351
分子生物学功能:
oxidase
