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Proteintech
CPEB1 Polyclonal Antibody
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产品信息
13274-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Echinoderm,
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CPEB1 Fusion Protein Ag3994 (188-486 aa encoded by BC035348)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody may recognize several bands, but only ~56 kDa band is the right one, other (40~50 kDa) is un-specific bands.
Immunogen sequence: WDLLEAPKD PFSIEREARL HRQAAAVNEA TCTWSGQLPP RNYKNPIYSC KVFLGGVPWD ITEAGLVNTF RVFGSLSVEW PGKDGKHPRC PPKGYVYLVF ELEKSVRSLL QACSHDPLSP DGLSEYYFKM SSRRMRCKEV QVIPWVLADS NFVRSPSQRL DPSRTVFVGA LHGMLNAEAL AAILNDLFGG VVYAGIDTDK HKYPIGSGRV TFNNQRSYLK AVSAAFVEIK TTKFTKKVQI DPYLEDSLCH ICSSQPGPFF CRDQVCFKYF CRSCWHWRHS MEGLRHHSPL MRNQKNRDSS (188-486 aa encoded by BC035348)
靶标信息
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the nuclear membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the nuclear membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CEBP; CPE-binding protein 1; CPE-BP1; CPEB; CPEB-1; Cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; mCPEB-1; MGC34136; MGC60106
基因别名: AU024112; CPE-BP1; CPEB; CPEB-1; CPEB1; h-CPEB; hCPEB-1; mCPEB
UniProt ID: (Human) Q9BZB8, (Mouse) P70166, (Rat) P0C279
Entrez Gene ID: (Human) 64506, (Mouse) 12877, (Rat) 293056
mRNA processing
translation
negative regulation of cell proliferation
positive regulation of neuron projection development
positive regulation of cell migration
cellular response to insulin stimulus
positive regulation of translation
mRNA transport
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to hypoxia
negative regulation of cytoplasmic translation
regulation of translation
synaptonemal complex assembly
negative regulation of translation
regulation of neuronal synaptic plasticity
