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CPN1 Antibody (PA5-96846) in WB
Western blot analysis of CPN1 in extracts of various cell lines. Samples were incubated with CPN1 Polyclonal antibody (Product # PA5-96846) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 20s.
产品信息
PA5-96846
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 209-458 of human CPN1 (NP_0012991)
偶联物
形式
Liquid
浓度
1.44 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2808648
产品详细信息
Immunogen sequence: FVLSANLHGG AVVANYPYDK SFEHRVRGVR RTASTPTPDD KLFQKLAKVY SYAHGWMFQG WNCGDYFPDG ITNGASWYSL SKGMQDFNYL HTNCFEITLE LSCDKFPPEE ELQREWLGNR EALIQFLEQV HQGIKGMVLD ENYNNLANAV ISVSGINHDV TSGDHGDYFR LLLPGIYTVS ATAPGYDPET VTVTVGPAEP TLVNFHLKRS IPQVSPVRRA PSRRHGVRAK VQPQARKKEM EMRQLQRGPA; Positive Samples: MCF-7, Raji, Mouse liver, Mouse pancreas, Rat brain; Cellular Location: extracellular space
靶标信息
CPN1 is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The protein is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This protein is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Anaphylatoxin inactivator; Arginine carboxypeptidase; carboxypeptidase K; Carboxypeptidase N catalytic chain; carboxypeptidase N catalytic subunit; Carboxypeptidase N polypeptide 1; carboxypeptidase N polypeptide 1 50 kD; Carboxypeptidase N small subunit; carboxypeptidase N, polypeptide 1; carboxypeptidase N, polypeptide 1, 50kD; CPN; FLJ40792; kininase I; Kininase-1; Lysine carboxypeptidase; Plasma carboxypeptidase B; SCPN; Serum carboxypeptidase N
基因别名: 0610011F20Rik; ACBP; CPN; CPN1; SCPN
UniProt ID: (Human) P15169, (Rat) Q9EQV8, (Mouse) Q9JJN5
Entrez Gene ID: (Human) 1369, (Rat) 365466, (Mouse) 93721
