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Proteintech
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Immunogen sequence: HVQRAEMLP KTSGTRATSL GRPEEEEDEL AHRCSSFMAP PVTDLGELRR RPGDMKTKME LLILETQAQV CQALAQVDGG ANFSVDRWER KEGGGGISCV LQDGCVFEKA GVSISVVHGN LSEEAAKQMR SRGKVLKTKD GKLPFCAMGV SSVIHPKNPH APTIHFNYRY FEVEEADGHK QWWFGGGCDL TPTYLNQEDA VHFHRTLKEA CDQHGPDLYP KFKKWCDDYF FIAHRGERRG IGGIFFDDLD SPSKEEVFRF VQSCARAVVP SYIPLVKKHC DDSFTPQEKL WQQLRRGRYV EFNLLYDRGT KFGLFTPGSR IESILMSLPL TARWEYMHSP SENSKEAEIL EVLRHPRDWV R (95-454 aa encoded by BC017210)
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: clone 560; coprogen oxidase; Coproporphyrinogen III oxidase, mitochondrial precursor (Coproporphyrinogenase) (Coprogen oxidase) (COX); coproporphyrinogen-III oxidase, mitochondrial; coproporphyrinogenase; COX; cpox {ECO:0000312|EMBL:AAI07665.1}; Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
基因别名: cac; CPO; CPOX; CPX; HCP; nct
UniProt ID: (Human) P36551, (Rat) Q3B7D0, (Mouse) P36552
Entrez Gene ID: (Human) 1371, (Rat) 304024, (Mouse) 12892