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Invitrogen
CRB1 Polyclonal Antibody
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产品信息
PA5-66373
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LLLALENSTYQ YIRVWLERGR LAMLTPNSPK LVVKFVLNDG NVHLISLKIK PYKIELYQSS QNLGFISAST WKIEKGDV
Highest antigen sequence identity to the following orthologs - mouse 75%, rat 68%.
靶标信息
CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: crumbs family member 1, photoreceptor morphogenesis associated; Crumbs homolog 1; Protein crumbs homolog 1
基因别名: CRB1; LCA8; RP12
UniProt ID: (Human) P82279
Entrez Gene ID: (Human) 23418
