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Proteintech
CREB3 Polyclonal Antibody
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产品信息
11275-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CREB3 Fusion Protein Ag1823 (1-395 aa encoded by BC009402)
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MELELDAGD QDLLAFLLEE SGDLGTAPDE AVRAPLDWAL PLSEVPSDWE VDDLLCSLLS PPASLNILSS SNPCLVHHDH TYSLPRETVS MDLESESCRK EGTQMTPQHM EELAEQEIAR LVLTDEEKSL LEKEGLILPE TLPLTKTEEQ ILKRVRRKIR NKRSAQESRR KKKVYVGGLE SRVLKYTAQN MELQNKVQLL EEQNLSLLDQ LRKLQAMVIE ISNKTSSSST CILVLLVSFC LLLVPAIYSS DTRGSLPAEH GVLSRQLRAL PSEDPYQLEL PALQSEVPKD STHQWLDGSD CVLQAPGNTS CLLHYMPQAP SAEPPLEWPF PDLFSEPLCR GPILPLQANL TRKGGWLPTG SPSVILQDRY SG (1-395 aa encoded by BC009402)
靶标信息
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: basic leucine zipper protein; CREB-3; cyclic AMP response element (CRE)-binding protein/activating transcription factor 1; Cyclic AMP-responsive element-binding protein 3; leucin zipper proitein; Leucine zipper protein; Luman; small leucine zipper protein; Transcription factor LZIP-alpha
基因别名: CREB3; LUMAN; LZIP; sLZIP
UniProt ID: (Human) O43889
Entrez Gene ID: (Human) 10488
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
cAMP response element binding
transcription from RNA polymerase II promoter
chemotaxis
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
viral process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of monocyte chemotaxis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
