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Proteintech
CREB3L1/OASIS Polyclonal Antibody
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产品信息
11235-2-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CREB3L1,OASIS Fusion Protein Ag1757 (170-519 aa encoded by BC015781)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: PHQAPGEMT QLPVIKAEPL EVNQFLKVTP EDLVQMPPTP PSSHGSDSDG SQSPRSLPPS SPVRPMARSS TAISTSPLLT APHKLQGTSG PLLLTEEEKR TLIAEGYPIP TKLPLTKAEE KALKRVRRKI KNKISAQESR RKKKEYVECL EKKVETFTSE NNELWKKVET LENANRTLLQ QLQKLQTLVT NKISRPYKMA ATQTGTCLMV AALCFVLVLG SLVPCLPEFS SGSQTVKEDP LAADGVYTAS QMPSRSLLFY DDGAGLWEDG RSTLLPMEPP DGWEINPGGP AEQRPRDHLQ HDHLDSTHET TKYLSEAWPK DGGNGTSPDF SHSKEWFHDR DLGPNTTIKL S (170-519 aa encoded by BC015781)
靶标信息
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system. May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BBF-2 homolog; cAMP responsive element binding protein 3-like 1; cAMP-responsive element-binding protein 3-like protein 1; Cyclic AMP-responsive element-binding protein 3-like protein 1; OASIS; old astrocyte specifically induced substance; Old astrocyte specifically-induced substance
基因别名: CREB3L1; OASIS; PSEC0238
UniProt ID: (Human) Q96BA8, (Mouse) Q9Z125, (Rat) Q66HA2
Entrez Gene ID: (Human) 90993, (Mouse) 26427, (Rat) 362165
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
protein binding
cAMP response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
osteoblast differentiation
transcription from RNA polymerase II promoter
multicellular organism development
endoplasmic reticulum unfolded protein response
extracellular matrix constituent secretion
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
transcription, DNA-templated
regulation of transcription, DNA-templated
response to unfolded protein
regulation of ossification
positive regulation of transcription from RNA polymerase II promoter
regulation of bone mineralization
