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Proteintech
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Immunogen sequence: MAGLSRGSA RALLAALLAS TLLALLVSPA RGRGGRDHGD WDEASRLPPL PPREDAARVA RFVTHVSDWG ALATISTLEA VRGRPFADVL SLSDGPPGAG SGVPYFYLSP LQLSVSNLQE NPYATLTMTL AQTNFCKKHG FDPQSPLCVH IMLSGTVTKV NETEMDIAKH SLFIRHPEMK TWPSSHNWFF AKLNITNIWV LDYFGGPKIV TPEEYYNVTV Q (1-220 aa encoded by BC008628)
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. CREG1 antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro.The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cellular repressor of E1A-stimulated genes 1; Protein CREG1
基因别名: AA755314; CREG; CREG1; UNQ727/PRO1409
UniProt ID: (Human) O75629, (Mouse) O88668
Entrez Gene ID: (Human) 8804, (Mouse) 433375, (Rat) 289185