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Invitrogen
CROT Polyclonal Antibody
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图: 1 / 2
CROT Antibody (PA5-103998) in ICC/IF
Immunofluorescent analysis of CROT in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and CROT polyclonal antibody (Product # PA5-103998) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-103998
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CROT(Accession Q9UKG9), corresponding to amino acid residues Q220-Q270.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CROT.
靶标信息
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4, 8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COT; Peroxisomal carnitine O-octanoyltransferase
基因别名: 1200003H03Rik; COT; CROT
UniProt ID: (Mouse) Q9DC50, (Rat) P11466
Entrez Gene ID: (Mouse) 74114, (Rat) 83842
generation of precursor metabolites and energy
lipid metabolic process
fatty acid metabolic process
fatty acid beta-oxidation
transport
carnitine metabolic process
fatty acid transport
coenzyme A metabolic process
response to drug
medium-chain fatty acid metabolic process
medium-chain fatty acid transport
response to organonitrogen compound
long-chain fatty acid transport
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