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Recommended positive controls: 293T, A431, HeLa, HepG2, Raji, mouse liver.
Predicted reactivity: Mouse (80%), Pig (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4, 8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: COT; peroxisomal carnitine acyltransferase; Peroxisomal carnitine O-octanoyltransferase
基因别名: 1200003H03Rik; COT; CROT
UniProt ID: (Human) Q9UKG9, (Mouse) Q9DC50
Entrez Gene ID: (Human) 54677, (Mouse) 74114