This antibody is predicted to react with rat and dog based on sequence homology.
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4, 8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
蛋白别名: COT; peroxisomal carnitine acyltransferase; Peroxisomal carnitine O-octanoyltransferase
基因别名: 1200003H03Rik; COT; CROT