应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:250-1:300 | - |
免疫细胞化学 (ICC/IF) |
Assay-dependent | - |
免疫沉淀 (IP) |
Assay-dependent | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Mouse / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
CSK-04 |
抗原 |
Recombinant fragment: VSDFGLTKEAS STQDTGKLPV KWTAPEALRE KKFSTKSDVW SFGILLWEIY SFGRVPYPRI PLKDVVPRVE KGYKMDAPDG CPPAVYEVMK NCWHLDAAMR PSFLQLREQL EHIKTHELHL, corresponding to amino acids 330-450 of Human CSK. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Protein A |
保存液 |
PBS |
内含物 |
15mM sodium azide |
保存条件 |
4° C |
RRID |
AB_1955628 |
MA1-34816 detects CSK from human, mouse samples.
C-terminal Src kinase (CSK) is a non-receptor protein tyrosine kinase that plays an important role in the regulation of cell growth, differentiation, migration, and immune responses. CSK phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases including LCK, SRC, HCK, FYN, LYN, CSK, and YES1. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft-associated protein PAG (Csk-binding protein).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-Src kinase; MGC117393; p50CSK; Protein-tyrosine kinase CYL; Protein-tyrosine kinase MPK-2; Tyrosine-protein kinase CSK
基因别名: AW212630; CSK; p50CSK
UniProt ID: (Human) P41240, (Mouse) P41241
Entrez Gene ID: (Human) 1445, (Mouse) 12988