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Invitrogen
CTAA16.88 (Votumumab Biosimilar) Recombinant Human Monoclonal Antibody
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产品信息
MA562574
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG3, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
CTAA16.88 is a member of the cancer/testis antigen (CTA) family, a group of proteins typically expressed in germ cells of the testis and aberrantly expressed in various cancers. Under normal physiological conditions, CTAA16.88 expression is largely restricted to immune-privileged tissues such as the testis, with little to no detectable expression in most adult somatic tissues. In malignancy, CTAA16.88 has been reported to be upregulated in certain tumor types, consistent with the characteristic CTA expression pattern. Because of its limited normal tissue distribution and tumor-associated expression, CTAA16.88 is considered a potential biomarker and immunotherapeutic target. CTAs, including CTAA16.88, are often immunogenic and capable of eliciting humoral and cellular immune responses in cancer patients, making them attractive candidates for cancer vaccines, adoptive T cell therapies, and antibody-based approaches. Although the precise biological function of CTAA16.88 is not fully characterized, cancer/testis antigens are generally implicated in processes such as cell cycle regulation, chromatin remodeling, and tumor progression. The restricted expression profile and tumor association of CTAA16.88 support its relevance in oncology research, particularly in studies focused on tumor immunology and targeted cancer therapy development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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