Immunogen sequence: GVHNTLAIVE NMAEFRPEMC TEGAQQGLLQ WLLKRLKAKM PFDANKLYCS EVLAILLQDN DENRELLGEL DGIDVLLQQL SVFKRHNPST A
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. Diseases associated with CTNNBL1 include Immunodeficiency 99 With Hypogammaglobulinemia And Autoimmune Cytopenias.
蛋白别名: Beta-catenin-like protein 1; catenin, beta like 1; NAP; nuclear associated protein; Nuclear-associated protein; RP5-1118M15.1; Testis development protein NYD-SP19
基因别名: C20orf33; CTNNBL1; dJ633O20.1; NAP; P14L; PP8304
UniProt ID: (Human) Q8WYA6
Entrez Gene ID: (Human) 56259