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Proteintech
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Immunogen sequence: GKEHKSEKE EEAGAAAVVD VAEGEEEEEE NEDLYYEGAM PEVSVLVLSR HSWPVASICH TLNPRTCLPS YLRGTLNRYS NFYNKSQSHP ALERGSQRRL QWTWLGWAEL QFGNQTLHVS TVQMWLLLYL NDLKAVSVES LLAFSGLSAD MLNQAIGPLT SSRGPLDLHE QKDIPGGVLK IRDGSKEPRS RWDIVRLIPP QTYLQAEGED GQNLEKRRNL LNCLIVRILK AHGDEGLHID QLVCLVLEAW QKGPCPPRGL VSSLGKGSAC SSTDVLSCIL HLLGKGTLRR HDDRPQVLSY AVPVTVMEPH TESLNPGSSG PNPPLTFHTL QIRSRGVPYA SCTATQSFST FR (1348-1698 aa encoded by B C033647)
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CUL-7; Cullin-7
基因别名: 3M1; CUL7; dJ20C7.5; KIAA0076
UniProt ID: (Human) Q14999
Entrez Gene ID: (Human) 9820