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Proteintech
CWC22 Polyclonal Antibody
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产品信息
26898-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CWC22 Fusion Protein Ag25466 (559-905 aa encoded by BC093954)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SLPWSVLEC IKLSEETTTS SSRIFVKIFF QELCEYMGLP KLNARLKDET LQPFFEGLLP RDNPRNTRFA INFFTSIGLG GLTDELREHL KNTPKVIVAQ KPDVEQNKSS PSSSSSASSS SESDSSDSDS DSSDSSSESS SEESDSSSIS SHSSASANDV RKKGHGKTRS KEVDKLIRNQ QTNDRKQKER RQEHGHQETR TERERRSEKH RDQNSRGSNW RDPITKYTSD KDVPSERNNY SRVANDRDQE MHIDLENKHG DPKKKRGERR NSFSENEKHT HRIKDSENFR RKDRSKSKEM NRKHSGSRSD EDRYQNGAER RWEKSSRYSE QSRESKKNQD RRREKSPA (559-905 aa encoded by BC093954)
靶标信息
Required for pre-mRNA splicing as component of the spliceosome (PubMed:12226669, PubMed:11991638, PubMed:22961380, PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961). Promotes exon-junction complex (EJC) assembly (PubMed:22959432, PubMed:22961380). Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CWC22 spliceosome-associated protein homolog; fSAPb; functional spliceosome-associated protein b; Nucampholin homolog; Pre-mRNA-splicing factor CWC22 homolog
基因别名: CWC22; EIF4GL; fSAPb; KIAA1604; NCM
UniProt ID: (Human) Q9HCG8
Entrez Gene ID: (Human) 57703
