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Invitrogen
CX3CR1 Monoclonal Antibody (2A9-1), FITC
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CX3CR1 Antibody (MA562400) in Flow
Flow cytometry (surface staining) of CX3CR1 in human peripheral whole blood. Samples were stained with CX3CR1 monoclonal antibody (Product # MA562400) using a dilution of 0.56 µg/mL. Separation of human CXCR1 positive CD3 negative lymphocytes (red-filled) from CXCR1 negative CD3 positive lymphocytes (black-dashed).
产品信息
MA562400
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Rat
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2A9-1
抗原
Human CX3CR1 transfectants.
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Size-exclusion chromatography
保存液
PBS, pH 7.4, with 0.2% BSA
内含物
15mM sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration an d adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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生物信息学
蛋白别名: Beta chemokine receptor-like 1; C-X3-C CKR-1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMK-BRL-1; CMK-BRL1; Cx3c; CX3C chemokine receptor 1; Fractalkine receptor; G protein-coupled receptor 13; G-protein coupled receptor 13; Scyd1; V28
基因别名: CCRL1; CMKBRL1; CMKDR1; CX3CR1; GPR13; GPRV28; V28
UniProt ID: (Human) P49238
Entrez Gene ID: (Human) 1524
positive regulation of neuroblast proliferation
microglial cell activation involved in immune response
negative regulation of chronic inflammatory response to non-antigenic stimulus
chemotaxis
cellular defense response
cell adhesion
G-protein coupled receptor signaling pathway
memory
response to wounding
viral process
negative regulation of angiogenesis
cerebral cortex cell migration
negative regulation of cell migration
positive regulation of angiogenesis
macrophage chemotaxis
chemokine-mediated signaling pathway
cellular response to lipopolysaccharide
cellular response to transforming growth factor beta stimulus
negative regulation of long-term synaptic potentiation
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
