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Leinco Technologies
CXCL9 Monoclonal Antibody (MIG-2F5-5), Functional Grade, In Vivo GOLD™
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产品信息
C793-100MG
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
宿主/亚型
Armenian hamster
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
MIG-2F5-5
抗原
Mouse plasmacytoid dendritic cells
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.2-7.4
内含物
no preservative
保存条件
4°C short term, -80°C long term
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Specificity: MIG-2F5-5 activity is directed against murine CXCL9 (monokine induced by gamma interferon, MIG).
Endotoxin Level: <1.0 EU/mg as determined by the LAL method.
Purity: ≥95% monomer by analytical SEC and >95% by SDS Page.
Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -70C. Avoid Repeated Freeze Thaw Cycles.
靶标信息
MIG, also known as CXCL9, is a T-cell chemoattractant inducible by gamma interferon that is a member of the CXC chemokine family of cytokines.This gene is mapped to 4q21. It is noted that, although the best-described activities of the chemokines are as chemotactic factors, chemokines also have an effect on T-cell activation, angiogenesis, and HIV infection. While most CXC chemokines are chemotactic for neutrophils, MIG and INP10 are unusual and similar in being CXC chemokines that are chemotactic for lymphocytes and inactive in neutrophils.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 9; CC motif chemokine; CCmotif chemokine; CXC; CXC motif chemokine; CXCL; gamma interferon-induced monokine; Gamma-interferon-induced monokine; M119; MIG; monokine induced by gamma interferon; Monokine induced by interferon-gamma; Protein m119; small inducible cytokine B subfamily (Cys-X-Cys), member 9; Small-inducible cytokine B9
基因别名: BB139920; CMK; crg-10; Cxcl9; Mig; MuMIG; Scyb9
UniProt ID: (Mouse) P18340
Entrez Gene ID: (Mouse) 17329
positive regulation of leukocyte chemotaxis
chemotaxis
inflammatory response
immune response
G-protein coupled receptor signaling pathway
T cell chemotaxis
response to lipopolysaccharide
regulation of cell proliferation
positive regulation of myoblast differentiation
defense response to virus
chemokine-mediated signaling pathway
positive regulation of myoblast fusion
