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This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: aryl hydrocarbon hydroxylase; CYPIIIA7; Cytochrome P450 3A7; cytochrome P450, family 3, subfamily A, polypeptide 7; cytochrome P450, subfamily IIIA, polypeptide 7; Cytochrome P450-HFLA; flavoprotein-linked monooxygenase; microsomal monooxygenase; P450HLp2; xenobiotic monooxygenase
基因别名: CP37; CYP3A7; CYPIIIA7; P-450(HFL33); P-450111A7; P450-HFLA
UniProt ID: (Human) P24462
Entrez Gene ID: (Human) 1551