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Invitrogen
CYP4A11/CYP4A22 Polyclonal Antibody
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CYP4A11/CYP4A22 Antibody (PA5-102018) in ICC/IF
Immunofluorescent analysis of CYP4A11/CYP4A22 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and CYP4A11/CYP4A22 polyclonal antibody (Product # PA5-102018) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Ale... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102018
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CYP4A11(Accession Q02928), corresponding to amino acid residues F150-C200.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Cytochrome P450 4A11/22.
靶标信息
Cytochrome P450 4A22 (CYP4A22) is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; alkane-1 monooxygenase; CYP4AII; CYPIVA11; Cytochrome P-450HK-omega; Cytochrome P450 4A11; cytochrome P450, family 4, subfamily A, polypeptide 11; cytochrome P450, subfamily IVA, polypeptide 11; Cytochrome P450HL-omega; Fatty acid omega-hydroxylase; Lauric acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase; major fatty acid-metabolizing P450; P450HL-omega; unnamed protein product
基因别名: CP4Y; CYP4A11; CYP4A2; CYP4AII; CYPIVA11
Entrez Gene ID: (Human) 1579
monooxygenase activity
iron ion binding
arachidonic acid monooxygenase activity
arachidonic acid epoxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
alkane 1-monooxygenase activity
heme binding
leukotriene-B4 20-monooxygenase activity
arachidonic acid omega-hydroxylase activity
long-chain fatty acid omega-hydroxylase activity
medium-chain fatty acid omega-hydroxylase activity
long-chain fatty acid metabolic process
kidney development
renal water homeostasis
pressure natriuresis
lipid metabolic process
fatty acid metabolic process
leukotriene metabolic process
arachidonic acid metabolic process
epoxygenase P450 pathway
oxylipin biosynthetic process
positive regulation of icosanoid secretion
leukotriene B4 catabolic process
linoleic acid metabolic process
icosanoid biosynthetic process
lauric acid metabolic process
sodium ion homeostasis
omega-hydroxylase P450 pathway
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