Invitrogen

CYP4Z1/CYP4Z2P Polyclonal Antibody

CYP4Z1/CYP4Z2P Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CYP4Z1/CYP4Z2P Antibody (PA5-67705) in IHC (P)

Immunohistochemical analysis of CYP4Z1/CYP4Z2P in paraffin-embedded human tonsil. 1) CYP4Z1/CYP4Z2P Polyclonal Antibody (Product # PA5-67705) was diluted at 1:200(4° overnight). 2) Tris-EDTA,pH9.0 was used for antigen retrieval. 3) Secondary antibody was diluted at 1:200 (room temperature, 30 min).

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产品信息

PA5-67705

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

免疫组化（石蜡） (IHC (P))

1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthesized peptide derived from human CYP4Z1/CYP4Z2.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2691468

靶标信息

The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.

仅用于科研。不用于诊断过程。未经明确授权不得转售。