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Proteintech
CYP7B1 Polyclonal Antibody
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产品信息
24889-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CYP7B1 Fusion Protein Ag19374 (96-403 aa encoded by BC136574)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: PFQYQLVIK NHKQLSFRVF SNKLLEKAFS ISQLQKNHDM NDELHLCYQF LQGKSLDILL ESMMQNLKQV FEPQLLKTTS WDTAELYPFC SSIIFEITFT TIYGKVIVCD NNKFISELRD DFLKFDDKFA YLVSNIPIEL LGNVKSIREK IIKCFSSEKL AKMQGWSEVF QSRQDVLEKY YVHEDLEIGA HHLGFLWASV ANTIPTMFWA MYYLLRHPEA MAAVRDEIDR LLQSTGQKKG SGFPIHLTRE QLDSLICLES SIFEALRLSS YSTTIRFVEE DLTLSSETGD YCVRKGDLVA IFPPVLHGD (96-403 aa encoded by BC136574)
靶标信息
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 24-hydroxycholesterol 7-alpha-hydroxylase; 25-hydroxycholesterol 7-alpha-hydroxylase; 25/26-hydroxycholesterol 7-alpha-hydroxylase; 3-hydroxysteroid 7-alpha hydroxylase; Cytochrome P450 7B1; cytochrome P450, 7b1; cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1; HCT-1; Hippocampal transcript 1 protein; Oxysterol 7-alpha-hydroxylase
基因别名: AW261589; CBAS3; CP7B; CYP7B1; D3Ertd552e; hct-1; SPG5A
UniProt ID: (Human) O75881, (Mouse) Q60991
Entrez Gene ID: (Human) 9420, (Mouse) 13123
bile acid biosynthetic process
cholesterol metabolic process
sterol metabolic process
negative regulation of intracellular estrogen receptor signaling pathway
B cell chemotaxis
positive regulation of epithelial cell proliferation
oxidation-reduction process
prostate gland epithelium morphogenesis
lipid metabolic process
digestion
memory
circadian rhythm
steroid metabolic process
