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Proteintech
Cadherin-13 Polyclonal Antibody
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产品信息
12618-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Cadherin-13 Fusion Protein Ag3295 (364-713 aa encoded by BC030653)
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TKKEFQATV EEGAVGVIVN LTVEDKDDPA TGAWRAAYTI INGNPGQSFE IHTNPQTNEG MLSVVKPLDY EISAFHTLLI KVENEDPLVP DVSYGPSSTA TVHITVLDVN EGPVFYPDPM MVTRQEDLSV GSVLLTVNAT DPDSLQHQTI RYSVYKDPAG WLNINPINGT VDTTAVLDRE STFVDNSVYT ALFLAIDSGN PPATGTGTLL ITLEDVNDNA PFIYPTVAEV CDDAKNLSVV ILGASDKDLH PNTDPFKFEI HKQAVPDKVW KISKINNTHA LVSLLQNLNK ANYNLPIMVT DSGKPPMTNI TDLRVQVCSC RNSKVDCNAA GALRFSLPSV LLLSLFSLAC L (364-713 aa encoded by BC030653)
靶标信息
The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAD13; cadherin 13, H-cadherin (heart); Cadherin-13; CD39 antigen-like 3; CD39-like 3; CD39L3; ecto-apyrase 3; ecto-ATPase 3; ecto-ATPDase 3; H-cadherin; H-cadherin (heart); HB6; Heart cadherin; heart-cadherin; NTPDase 3; NTPDase-3; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated cadherin; truncated-cadherin
基因别名: 4932416G01Rik; CDH13; CDHH; Cdht; P105; T-cadherin; Tcad
UniProt ID: (Human) P55290, (Mouse) Q9WTR5
Entrez Gene ID: (Human) 1012, (Mouse) 12554
mitotic cell cycle
positive regulation of endothelial cell proliferation
positive regulation of cell-matrix adhesion
sprouting angiogenesis
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of cell adhesion
Rho protein signal transduction
negative regulation of cell proliferation
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Rac protein signal transduction
lamellipodium assembly
regulation of endocytosis
positive regulation of cell migration
adherens junction organization
regulation of epidermal growth factor receptor signaling pathway
endothelial cell migration
keratinocyte proliferation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
positive regulation of calcium-mediated signaling
positive regulation of positive chemotaxis
localization within membrane
low-density lipoprotein particle mediated signaling
regulation of cell growth
cell adhesion
