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Invitrogen
Calbindin D28K Monoclonal Antibody (401025)
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Calbindin D28K Antibody (MA5-24135) in IHC (P)
Immunohistochemical analysis of Calbindin D28K in immersion fixed paraffin-embedded sections of human brain (cerebellum). Samples were incubated in Calbindin D28K monoclonal antibody (Product # MA5-24135) using a dilution of 25 µg/mL overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-24135
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
401025
抗原
E. coli-derived recombinant human Calbindin D Met1-Asn261
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human S100P.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: calbindin 1, (28kD); calbindin 1, 28kDa; calbindin 27; calbindin D28; calbindin-D28k; retrovirus-like H primer binding sequence protein; RTVL-H protein; unnamed protein product; vitamin D-dependent calcium-binding protein, avian-type
基因别名: CALB; D-28K
UniProt ID: (Human) P05937
Entrez Gene ID: (Human) 793
learning or memory
short-term memory
long-term memory
retina layer formation
response to auditory stimulus
metanephric part of ureteric bud development
regulation of synaptic plasticity
calcium ion homeostasis
retina development in camera-type eye
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
cochlea development
regulation of presynaptic cytosolic calcium ion concentration
regulation of postsynaptic cytosolic calcium ion concentration
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