Invitrogen

Calcitonin Monoclonal Antibody (13B9)

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Calcitonin Antibody in Western Blot (WB) — Detection of human recombinant PCT in Western blotting by monoclonal antibodies specific to calcitonin following 15% SDS-PAGE in reducing conditions. Antigen loaded - 100 ng/lane; Lane 1: Calcitonin Monoclonal Antibody (13B9) (Product # MA1-20285); Lane 2: Calcitonin Monoclonal Antibody (13f2) (Product # MA1-20890); Lane 3: Calcitonin antibody [13G11] (Product # MA1-20891); Lane 4: Calcitonin antibody [14A2] (Product # MA1-20290); Lane 5: Calcitonin antibody [16B5] (Product # MA1-20288); Lane 6: Calcitonin Monoclonal Antibody (24B2) (Product # MA1-20291).

Calcitonin Antibody in ELISA (ELISA) — Titration curve of Calcitonin Monoclonal Antibody (13B9) (Product # MA1-20285) in indirect ELISA. Antigen: Calcitonin human recombinant - 0.02 µg/well.

产品信息

MA1-20285

应用	建议稀释比	已发表文章
免疫印迹 (WB)	Assay-dependent	-
酶联免疫吸附实验 (ELISA)	Assay-dependent	-

产品规格
种属反应	Human
宿主/亚型	Mouse / IgG2a
分类	Monoclonal
类型	Antibody
克隆号	13B9
抗原	Recombinant, full length, human calcitonin protein.
偶联物	Unconjugated
形式	Liquid
浓度	3.6 mg/mL
纯化类型	Protein A
保存液	PBS, pH 7.4
内含物	0.09% sodium azide
保存条件	4° C
RRID	AB_557859

产品详细信息

This antibody may be used in a sandwich ELISA when paired with MA1-20291 as the capture antibody.

靶标信息

Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Alpha CGRP; Alpha type CGRP; Alpha-type CGRP; Calcitonin; calcitonin 1; Calcitonin carboxyl-terminal peptide; calcitonin gene related peptide 1; Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; calcitonin-related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; CCP; CGRP-I; Katacalcin; katacalcin (KC); PDN-21

基因别名: CALC1; CALCA; CGRP; CGRP-I; CGRP1; CT; KC; PCT

UniProt ID: (Human) P06881

Entrez Gene ID: (Human) 796

分子生物学功能: peptide hormone

功能

vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure regulation of heart rate monocyte chemotaxis inflammatory response adenylate cyclase-activating G-protein coupled receptor signaling pathway activation of adenylate cyclase activity positive regulation of cytosolic calcium ion concentration neuropeptide signaling pathway embryo implantation aging feeding behavior response to heat negative regulation of ossification negative regulation of neurological system process activation of protein kinase activity cellular protein metabolic process positive regulation of adenylate cyclase activity positive regulation of ossification negative regulation of bone resorption negative regulation of transcription, DNA-templated negative regulation of smooth muscle contraction response to pain detection of temperature stimulus involved in sensory perception of pain positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway cellular response to tumor necrosis factor cellular response to nerve growth factor stimulus

参与通路

hormone activity protein binding calcitonin receptor binding identical protein binding

Calcitonin Monoclonal Antibody (13B9)

产品信息

MA1-20285

免疫印迹 (WB)

酶联免疫吸附实验 (ELISA)

种属反应

宿主/亚型

分类

类型

克隆号

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

RRID

产品详细信息

靶标信息

篇参考文献 (0)

生物信息学

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