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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
酶联免疫吸附实验 (ELISA) |
Assay-Dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG2a, kappa |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
2G2 |
抗原 |
CAPN11 (NP_008989, 557 a.a. ~ 651 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4 |
内含物 |
no preservative |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2576539 |
Peptide Sequence: LLNRMAIKFK SFKTKGFGLD ACRCMINLMD KDGSGKLGLL EFKILWKKLK KWMDIFRECD QDHSGTLNSY EMRLVIEKAG IKLNNKVMQV LVARY
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calcium-activated neutral proteinase 11; Calpain-11; CANP 11; HIP2; LIG
基因别名: calpain11; CAPN11
UniProt ID: (Human) Q9UMQ6
Entrez Gene ID: (Human) 11131
分子生物学功能:
cysteine protease
