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Product Details
MA5-21265
产品规格
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2G2
Immunogen
CAPN11 (NP_008989, 557 a.a. ~ 651 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2576539
Product Specific Information
Peptide Sequence: LLNRMAIKFK SFKTKGFGLD ACRCMINLMD KDGSGKLGLL EFKILWKKLK KWMDIFRECD QDHSGTLNSY EMRLVIEKAG IKLNNKVMQV LVARY
Target Information
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: Calcium-activated neutral proteinase 11; Calpain-11; CANP 11; HIP2; LIG
Gene Aliases: calpain11; CAPN11
UniProt ID: (Human) Q9UMQ6
Entrez Gene ID: (Human) 11131
Molecular Function:
cysteine protease
Performance Guarantee
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