Search
Alomone Labs, LTD
Cannabinoid Receptor 2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 4
Cannabinoid Receptor 2 Antibody (ACR-002-200UL) in IHC (P)
Expression of CB2 receptor in rat dermis - Immunohistochemical staining of paraffin embedded section of rat dermis using Anti-Cannabinoid Receptor2 Antibody (#ACR-002), (1:100). CB2 is expressed in sebaceous glands and ducts of sweat glands in the reticular dermis. Hematoxilin is used as the counterstain.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
ACR-002-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)DRQVPGIARMRLDVR, corresponding to amino acid residues 228-242 of rat CB2 receptor, 3rd intracellular loop
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.65 mg/mL
规格
130 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Cannabinoid Receptor 2; cannabinoid receptor 2 (macrophage); cannabinoid receptor 2 (spleen); CB2 receptor; CB2R; CNR3; G protein coupled receptor; HCB2; HGNC:2160; OTTHUMP00000044841; peripheral cannabinoid receptor; RP11-4M23.1; unnamed protein product
基因别名: CB-2; CB2; CB2-R; CB2C; CNR2C; CX5; rCB2
UniProt ID: (Human) P34972, (Mouse) P47936, (Rat) Q9QZN9
Entrez Gene ID: (Human) 1269, (Mouse) 12802, (Rat) 57302
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
leukocyte chemotaxis
negative regulation of synaptic transmission, GABAergic
response to lipopolysaccharide
negative regulation of mast cell activation
cannabinoid signaling pathway
positive regulation of osteoblast differentiation
negative regulation of action potential
negative regulation of nitric-oxide synthase activity
trans-synaptic signaling by endocannabinoid
trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
response to amphetamine
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
response to ethanol
regulation of synaptic transmission, GABAergic
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
