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Peptide Sequence: VQAESSNYPC LVPVKWGGNC QKDRQSPINI VTTKAKVDKK LGRFFFSGYD KKQTWTVQNN GHSVMMLLEN KASISGGGLP APYQAKQLHL HWSDLPYKGS
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
蛋白别名: CA-IV; Carbonate dehydratase IV; Carbonic anhydrase 4; Carbonic anhydrase IV; carbonic dehydratase IV
基因别名: CA4; CAIV; Car4; RP17
UniProt ID: (Human) P22748
Entrez Gene ID: (Human) 762