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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:50 | - |
免疫细胞化学 (ICC/IF) |
1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG2a |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
OTI2A3 |
抗原 |
Recombinant protein expressed in E.coli corresponding to amino acids 1-419 of CPA-1. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.32 mg/mL |
纯化类型 |
Affinity Chromatography |
保存液 |
PBS, pH 7.3, with 1% BSA, 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2722914 |
CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Carboxypeptidase A1; carboxypeptidase A1 (pancreatic); pancreatic carboxypeptidase A
基因别名: CPA; CPA1
UniProt ID: (Human) P15085
Entrez Gene ID: (Human) 1357
分子生物学功能:
metalloprotease
