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产品信息
MA1-22697
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
Assay-dependent | - |
酶联免疫吸附实验 (ELISA) |
Assay-dependent | - |
亲和纯化 (AP) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG2a |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
1A2 |
抗原 |
Isolated slow skeletal isoform of TnC |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2 mg/mL |
纯化类型 |
Protein A |
保存液 |
PBS, pH 7.4 |
内含物 |
0.09% sodium azide |
保存条件 |
4° C, do not freeze |
RRID |
AB_2240780 |
产品详细信息
MA1-22697 detects Cardiac Troponin C in Human samples.
靶标信息
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiac 3; cardiac troponin C; CMD1FF; CMD2A; CMH7; MGC116817; RCM1; slow twitch skeletal/cardiac muscle troponin C; TN-C; Tn1; Tni; TNN I3; TNNC 1; TNNI3; troponin C type 1 (slow); Troponin C, slow skeletal and cardiac muscles; troponin C1, slow; Troponin I cardiac; TroponinI
基因别名: CMD1Z; CMH13; TN-C; TNC; TNNC; TNNC1
UniProt ID: (Human) P63316
Entrez Gene ID: (Human) 7134
diaphragm contraction
skeletal muscle contraction
regulation of muscle contraction
response to metal ion
transition between fast and slow fiber
muscle filament sliding
regulation of muscle filament sliding speed
regulation of ATPase activity
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
