Invitrogen

Cardiac Troponin T Monoclonal Antibody (9G6)

产品信息

MA1-22705

应用	建议稀释比	已发表文章
酶联免疫吸附实验 (ELISA)	Assay-dependent	-
亲和纯化 (AP)	Assay-dependent	-

产品规格
种属反应	Human
宿主/亚型	Mouse / IgG1
分类	Monoclonal
类型	Antibody
克隆号	9G6
抗原	Full length native protein (purified) (Human). 查看免疫原
偶联物	Unconjugated
形式	Liquid
浓度	5.6 mg/mL
纯化类型	Protein A
保存液	PBS, pH 7.4
内含物	0.09% sodium azide
保存条件	4° C, do not freeze
RRID	AB_561849

产品详细信息

MA1-22705 detects Cardiac Troponin T in Human samples.

靶标信息

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: Cardiac muscle troponin T; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; cTnT; MGC3889; TnTc; troponin T type 2 (cardiac); Troponin T, cardiac muscle; Troponin T2; troponin T2, cardiac; truncated cardiac troponin T

基因别名: CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TNNT2; TnTC

UniProt ID: (Human) P45379

Entrez Gene ID: (Human) 7139

分子生物学功能: actin binding motor protein

功能

regulation of heart contraction muscle filament sliding negative regulation of ATPase activity positive regulation of ATPase activity regulation of muscle filament sliding speed protein heterooligomerization response to calcium ion actin crosslink formation ventricular cardiac muscle tissue morphogenesis cardiac muscle contraction

参与通路

actin binding protein binding tropomyosin binding troponin C binding protein binding, bridging troponin I binding

Cardiac Troponin T Monoclonal Antibody (9G6)

产品信息

MA1-22705

酶联免疫吸附实验 (ELISA)

亲和纯化 (AP)

种属反应

宿主/亚型

分类

类型

克隆号

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

RRID

产品详细信息

靶标信息

篇参考文献 (0)

生物信息学

性能保障

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