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Invitrogen
Cardiotin Monoclonal Antibody
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产品信息
OMA1-06031
产品规格
宿主/亚型
Mouse
/ IgM
分类
Monoclonal
类型
Antibody
抗原
100 kDa Cardiotin subunit.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
保存条件
4°C
运输条件
Wet ice
产品详细信息
OMA1-06031 detects Cardiotin from human and porcine samples.
OMA1-06031 has been successfully used in Western blot and immunohistochemistry applications.
The OMA1-06031 immunogen is the 100 kDa Cardiotin subunit.
靶标信息
Cardiotin is a recently discovered, high molecular weight protein complex (~300 kDa) located in the longitudinal SR of cardiomyocytes. The cardiotin complex exists as 60 kDa and 100 kDa subunits. Both subunits contain the same amino-terminal 14 amino-acid sequence, and show high homology to human skeletal muscle alpha-actin. The tetrameric configuration of the cardiotin protein complex suggests that it exists as a transmembrane complex with the N-terminus at the cytoplasmic side of the membrane, able to interact with actin. Immunofluorescence studies colocalize cardiotin with SERCA 2a ATPase in the longitudinal sarcoplasmic reticulum (SR), although cardiotin is not expressed in junctional SR with SERCA 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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