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Invitrogen
Carprofen Recombinant Mouse Monoclonal Antibody (4C10)
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Carprofen Antibody (MA566592) in SDS-PAGE
SDS-PAGE characterization of Carprofen under reducing conditions. Lane M: Protein marker (kDa); Lane CPF: Purified Carprofen Recombinant Monoclonal (Product # MA566592). Carprofen showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-678.
产品信息
MA566592
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4C10
抗原
Conjugate of CPF hapten and KLH.
偶联物
形式
Liquid
浓度
5.6 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) primarily used in veterinary medicine to relieve pain and inflammation in animals. It functions by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the synthesis of prostaglandins, thus reducing inflammation and pain. Carprofen's molecular structure allows it to interact with lipid bilayers, influencing its orientation and position within the membrane interface, which is crucial for its docking to target enzymes like gamma-secretase. Recent studies have explored carprofen analogues as potential sirtuin inhibitors, combining its chemical features with other compounds to enhance therapeutic effects, such as increasing acetylation levels of proteins like p53 and alpha-tubulin. Additionally, efforts to improve carprofen's solubility have led to its intercalation into structures like Zn2Al LDH, enhancing its bioavailability. These advancements highlight carprofen's versatility in therapeutic applications beyond its traditional use.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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