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Proteintech
Caspase 6/p18/p11 Polyclonal Antibody
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产品信息
10198-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Caspase 6/p18/p11 Fusion Protein Ag0257 (59-222 aa encoded by BC000305)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LTLPERRGT CADRDNLTRR FSDLGFEVKC FNDLKAEELL LKIHEVSTVS HADADCFVCV FLSHGEGNHI YAYDAKIEIQ TLTGLFKGDK CHSLVGKPKI FIIQACRGNQ HDVPVIPLDV VDNQTEKLDT NITEVDAASV YTLPAGADFL MCYSVAEGYY SHRET (59-222 aa encoded by B C000305)
靶标信息
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Apoptotic protease Mch-2; CASP-6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; Caspase-6
基因别名: CASP-6; CASP6; MCH2
UniProt ID: (Human) P55212, (Mouse) O08738
Entrez Gene ID: (Human) 839, (Mouse) 12368, (Rat) 83584
proteolysis
apoptotic process
cellular component disassembly involved in execution phase of apoptosis
epithelial cell differentiation
regulation of apoptotic process
lens development in camera-type eye
acute inflammatory response to non-antigenic stimulus
response to heat
response to glucose
response to organic substance
response to metal ion
response to iron ion
response to organonitrogen compound
response to gamma radiation
response to estradiol
response to testosterone
response to cytokine
response to hydrogen peroxide
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of retinal cell programmed cell death
