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Alomone Labs, LTD
CatSper4 (extracellular) Polyclonal Antibody
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产品信息
ACC-304-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)NSYLGQKHYELFSTID, corresponding to amino acid residues 90-105 of mouse CatSper4, 1st extracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
CatSper4, is a protein which in humans is encoded by the CATSPER4 gene. CatSper1 is a member of thecation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells. Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cation channel of sperm 4; Cation channel sperm-associated protein 4; cation channel, sperm associated 4; CatSper4; channel, sperm associated 4; CTSR4
基因别名: 4933412L05; Catsper4; RGD1565213
UniProt ID: (Mouse) Q8BVN3
Entrez Gene ID: (Mouse) 329954, (Rat) 362623
transport
ion transport
sodium ion transport
calcium ion transport
multicellular organism development
spermatogenesis
cell differentiation
sperm motility
regulation of ion transmembrane transport
sperm capacitation
transmembrane transport
calcium ion import
calcium ion transmembrane transport
membrane depolarization during action potential
