Proteintech

Cathepsin F Polyclonal Antibody

Name: Cathepsin F Polyclonal Antibody
Brand: Proteintech
SKU: 11055-1-AP

3 篇参考文献

查看其他8个Cathepsin F抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (10)

Cathepsin F Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 10

Cathepsin F Antibody (11055-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using 11055-1-AP (Cathepsin F antibody at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

Cathepsin F Antibody in Western Blot (WB)

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Immunogen image

Immunogen Image Cathepsin F Polyclonal Antibody

产品信息

11055-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化 (IHC)

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Cathepsin F Fusion Protein Ag1521 (136-484 aa encoded by BC011682)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: EPKSAFTQG SAMISSLSQN HPDNRNETFS SVISLLNEDP LSQDLPVKMA SIFKNFVITY NRTYESKEEA RWRLSVFVNN MVRAQKIQAL DRGTAQYGVT KFSDLTEEEF RTIYLNTLLR KEPGNKMKQA KSVGDLAPPE WDWRSKGAVT KVKDQGMCGS CWAFSVTGNV EGQWFLNQGT LLSLSEQELL DCDKMDKACM GGLPSNAYSA IKNLGGLETE DDYSYQGHMQ SCNFSAEKAK VYINDSVELS QNEQKLAAWL AKRGPISVAI NAFGMQFYRH GISRPLRPLC SPWLIDHAVL LVGYGNRSDV PFWAIKNSWG TDWGEKGYYY LHRGSGACGV NTMASSAVVD (136-484 aa encoded by BC011682)

靶标信息

Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

仅用于科研。不用于诊断过程。未经明确授权不得转售。