Human Cdc25C shares 78.2% amino acid (aa) sequence identity with mouse Cdc25C.
Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
M-phase inducer phosphatase 3is an enzyme that in humans is encoded by theCDC25Cgene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
蛋白别名: Dual specificity phosphatase Cdc25C; EC 184.108.40.206; M-phase inducer phosphatase 3; mitosis inducer CDC25; MPIP3; OTTHUMP00000159490; OTTHUMP00000224012; OTTHUMP00000224013; OTTHUMP00000224016; phosphotyrosine phosphatase; protein phosphatase 1, regulatory subunit 60
基因别名: CDC25; CDC25C; PPP1R60
UniProt ID: (Human) P30307
分子生物学功能: protein phosphatase