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产品信息
PA5-50092
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:3,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthesized peptide derived from internal of human CDC40. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635545 |
产品详细信息
The antibody detects endogenous levels of total CDC40 / PRP17 protein.
靶标信息
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; hPRP17; pre-mRNA splicing factor 17; Pre-mRNA-processing factor 17; PRP17 homolog
基因别名: 1200003H23Rik; CDC40; EHB3; PRP17; PRPF17
UniProt ID: (Human) O60508, (Mouse) Q9DC48
Entrez Gene ID: (Human) 51362, (Mouse) 71713, (Rat) 361859
分子生物学功能:
RNA metabolism protein
RNA processing factor
RNA splicing factor
nucleic acid metabolism protein
