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产品信息
PA5-50002
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:3,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthesized peptide derived from N-terminal of human CDC42EP3. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635455 |
产品详细信息
The antibody detects endogenous levels of total CDC42EP3 / BORG2 protein.
靶标信息
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Binder of Rho GTPases 2; CDC42 effector protein (Rho GTPase binding) 3; Cdc42 effector protein 3; CRIB-containing BORG2 protein; MSE55-related Cdc42-binding protein; MSE55-related protein
基因别名: 3200001F04Rik; AA986861; BORG2; CDC42EP3; CEP3; UB1
UniProt ID: (Human) Q9UKI2, (Mouse) Q9CQC5
Entrez Gene ID: (Human) 10602, (Mouse) 260409, (Rat) 313838
