FIGURE: 1 / 2
Peptide Sequence: VPRRNGAAGP HSPDPLLDEQ AFGDLTDLPV VPKATYGLKH AESIMSFHID LGPSMLGDVL SIM
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
Protein Aliases: Binder of Rho GTPases 4; CDC42 effector protein (Rho GTPase binding) 4; Cdc42 effector protein 4; MGC17125; MGC3740
Gene Aliases: BORG4; CDC42EP4; CEP4; KAIA1777
UniProt ID: (Human) Q9H3Q1
Entrez Gene ID: (Human) 23580