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Invitrogen
Cdc6 Polyclonal Antibody
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Cdc6 Antibody (PA5-29167) in ICC/IF
Immunofluorescent analysis of CDC6 showing staining in the cytoplasm of HeLa cells. HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using a CDC6 polyclonal antibody (Product # PA5-29167) diluted at 1:500. Blue: Hoechst 33343 staining.
产品信息
PA5-29167
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 278 of Human CDC6
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA5-29167 targets CDC6 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29167 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 278 of Human CDC6.
靶标信息
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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