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Invitrogen
Cdc7 Monoclonal Antibody (SPM171)
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产品信息
MA1-21285
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
SPM171
抗原
Recombinant full length protein (Human).
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
4°C
运输条件
Wet ice
RRID
产品详细信息
MA1-21285 detects Cdc7 Kinase in Human samples.
MA1-21285 has been successfully used in Immunohistochemistry (Paraffin), Immunoprecipitation and Western Blot procedures.
MA1-21285 immunogen corresponds to Recombinant full length protein (Human)..
靶标信息
CDC7 is a cell division cycle 7 homolog protein that is critical for the G1/S transition and is also essential for initiation of DNA replication as cell division occurs. CDC7 is expressed in many normal tissues, but the overexpression of CDC7 may be associated with neoplastic transformation for some tumors and transformed cell lines. CDC7/DBF4 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 that evolved to integrate several protein kinase. CDC7 encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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