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Invitrogen
Cefoperazone Recombinant Mouse Monoclonal Antibody (2B8)
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Cefoperazone Antibody (MA566589) in SDS-PAGE
SDS-PAGE characterization of Cefoperazone under reducing conditions. Lane M: Protein marker (kDa); Lane CEPZ: Purified Cefoperazone Recombinant Monoclonal (Product # MA566589). Cefoperazone showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-429.
产品信息
MA566589
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2B8
抗原
Conjugate of CEPZ hapten and KLH.
偶联物
形式
Liquid
浓度
8.1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Cefoperazone is a third-generation cephalosporin antibiotic known for its broad-spectrum antibacterial activity, particularly effective against gram-negative organisms such as Pseudomonas aeruginosa, and some anaerobic bacteria including Bacteroides fragilis. It is administered parenterally, either intravenously or intramuscularly, and is often combined with sulbactam to enhance its efficacy against beta-lactamase-producing strains. The antibiotic functions by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Cefoperazone is structurally characterized by a beta-lactam ring, and its minimal inhibitory concentrations are influenced by high inoculum concentrations of beta-lactamase-producing strains. It is used in treating infections in various body locations, including the respiratory tract, abdomen, skin, and female genital tracts. However, it can cause hypoprothrombinemia and bleeding due to its methylthiotetrazole side chain. The addition of sulbactam extends its spectrum to include Acinetobacter species. It is important to note that cefoperazone's efficacy and safety have been compared to other cephalosporins in treating bacterial infections, demonstrating its clinical utility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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